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Title: Detection of Dopamine Based on Aptamer-Modified Graphene Microelectrode. Author: Zhang C, Chen T, Ying Y, Wu J. Journal: Sensors (Basel); 2024 May 05; 24(9):. PubMed ID: 38733043. Abstract: In this paper, a novel aptamer-modified nitrogen-doped graphene microelectrode (Apt-Au-N-RGOF) was fabricated and used to specifically identify and detect dopamine (DA). During the synthetic process, gold nanoparticles were loaded onto the active sites of nitrogen-doped graphene fibers. Then, aptamers were modified on the microelectrode depending on Au-S bonds to prepare Apt-Au-N-RGOF. The prepared microelectrode can specifically identify DA, avoiding interference with other molecules and improving its selectivity. Compared with the N-RGOF microelectrode, the Apt-Au-N-RGOF microelectrode exhibited higher sensitivity, a lower detection limit (0.5 μM), and a wider linear range (1~100 μM) and could be applied in electrochemical analysis fields.[Abstract] [Full Text] [Related] [New Search]