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  • Title: Exploiting specific properties of squid pens for the preparation of oligochitosan hydrochloride.
    Author: Bezrodnykh EA, Blagodatskikh IV, Vyshivannaya OV, Berezin BB, Tikhonov VE.
    Journal: Carbohydr Res; 2024 Jun; 540():109140. PubMed ID: 38759342.
    Abstract:
    Herein, we describe in first the application of squid pens for the preparation of pharmaceutical-grade oligochitosan hydrochloride with the physicochemical characteristics corresponding with the requirements of the European Pharmacopoeia. It is shown that the use of specific properties of squid pens as a source of parent chitosan allows preparing the product with a high yield at relatively moderate process conditions used for squid pens treatments and chitosan depolymerization.
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