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  • Title: The role of time to positive blood cultures in enhancing the predictive capability of DENOVA score for diagnosing infective endocarditis in patients with Enterococcus faecalis bacteremia.
    Author: Pérez-Rodríguez MT, Lima O, Garrido M, Rincón A, Martínez-Lamas L, Pérez-González A, Araújo A, Amoedo A, Sousa A, López A, Cabrera X, Rubianes M.
    Journal: Eur J Clin Microbiol Infect Dis; 2024 Jul; 43(7):1481-1486. PubMed ID: 38763988.
    Abstract:
    DENOVA-score is useful to stratify the risk of infective endocarditis (IE) in Enterococcus faecalis bacteremia. Recently, time to positive (TTP) of blood cultures has also been related with a higher risk of IE. The objective was to evaluate DENOVA- score with TTP to improve its specificity. We performed a retrospective, case-control study in adult patients with E. faecalis bacteremia. Thirty-nine patients with definite E. faecalis IE and 82 with E. faecalis bacteremia were included. The addition of a TTP ≤ 8 h to DENOVA-score did not improve the diagnostic accuracy of this score.
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