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  • Title: Clinical features and followup study of HLA-B27 positive patients presenting with peripheral arthritis.
    Author: Sambrook P, McGuigan L, Champion D, Edmonds J, Fleming A, Portek I.
    Journal: J Rheumatol; 1985 Jun; 12(3):526-8. PubMed ID: 3876436.
    Abstract:
    A comparison was made between HLA-B27 positive patients with peripheral arthritis and patients with ankylosing spondylitis (AS). The distribution of peripheral joint involvement in HLA-B27 positive seronegative arthritis was not the same as that in AS; significant differences were also noted in the sex ratio and incidence of uveitis. Followup of the patients with peripheral arthritis revealed that 25% had developed a further criterion for Reiter's syndrome, 45% had persistent seronegative arthritis and in 55% the arthritis had resolved.
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