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  • Title: Akinetic mutism and parkinsonism associated with obstructive hydrocephalus.
    Author: Berger L, Gauthier S, Leblanc R.
    Journal: Can J Neurol Sci; 1985 Aug; 12(3):255-8. PubMed ID: 3876872.
    Abstract:
    We report the case of a patient with idiopathic aqueductal stenosis and hydrocephalus who had several episodes of akinetic mutism, each preceded by shunt malfunction, that resolved with shunt revision. She also developed a parkinson's syndrome resistant to shunt revision but responsive to antiparkinsonian medications. The parkinson's syndrome and the episodes of akinetic mutism may be related to a reduction of dopaminergic input to the striatum and to the cingulate and frontal cortex brought about or worsened by ventricular dilatation.
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