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  • Title: Use of an emulsion formulation of propofol ('Diprivan') in intravenous anaesthesia for termination of pregnancy. A comparison with methohexitone.
    Author: Cundy JM, Arunasalam K.
    Journal: Postgrad Med J; 1985; 61 Suppl 3():129-31. PubMed ID: 3877280.
    Abstract:
    The use of an emulsion formulation of 2,6-diisopropylphenol (propofol) for induction and maintenance of anaesthesia was compared with methohexitone in 60 patients undergoing termination of pregnancy. In the dosages chosen the two agents appeared to be equi-potent. Propofol was associated with a statistically significant superior quality of anaesthesia. Apnoea of greater than 30 s occurred in 8 patients who received propofol but in none of the patients who received methohexitone. Methohexitone was associated with coughing and laryngospasm in 5 patients. There was no difference in the recovery times between the 2 groups but the patients who received methohexitone were significantly more drowsy post-operatively.
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