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  • Title: Observations on regional cerebral blood flow in cortical and subcortical structures during language production in normal man.
    Author: Wallesch CW, Henriksen L, Kornhuber HH, Paulson OB.
    Journal: Brain Lang; 1985 Jul; 25(2):224-33. PubMed ID: 3877544.
    Abstract:
    Regional cerebral blood flow (rCBF) was studied by single photon emission computerized tomography (SPECT) of inhaled xenon-133 in six normal volunteers during various language, articulatory, and control conditions. Language production increased rCBF in predominantly left-sided cortical and subcortical areas. The involved regions were anatomically related to a left frontal area (Broca's), to both caudate nuclei, to a left thalamic/pallidal area, and bilaterally in retrorolandic areas. The failure to demonstrate lateralized retrorolandic activity is thought to reflect the complexity of the tasks.
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