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  • Title: [Effect of the C1q subcomponent of complement on thrombocyte adhesion and spreading].
    Author: Lozhkina AN, Aleshkin VA.
    Journal: Biull Eksp Biol Med; 1985 Dec; 100(12):694-6. PubMed ID: 3878161.
    Abstract:
    In vitro experiments have shown that C1q at a concentration of 8-250 mkg/ml produced a 1.5-2-fold increase in platelet adhesion to glass. Low doses (4-60 mkg/ml) enhanced platelet splitting 2-3-fold. C1q did not cause platelet aggregation or change ADP-, adrenalin- and thrombin-induced aggregation. C1q participation in the induction of immune response is suggested.
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