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  • Title: [Delayed hypersensitivity reaction to rat xenoantigens in mice].
    Author: Liadova IV, Cherniakhovskaia IIu.
    Journal: Biull Eksp Biol Med; 1985 Dec; 100(12):762-5. PubMed ID: 3878164.
    Abstract:
    A scheme of delayed-type hypersensitivity (DTH) to xenogeneic lymphoid cells induced in mice was suggested. Subcutaneous injection of normal mice with 5 X 10(6) rat spleen cells in a complete Freund's adjuvant with the results evaluated 5 days after was found the optimal condition for DTH development. Mediated by T lymphocytes the response was shown to be maximal 24 hours after the challenge.
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