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  • Title: Establishment and partial characterisation of a human fibrosarcoma cell line MR-83.
    Author: Stuckly K, Kiddle R, Leversha M, Ellis WM, Ekert H.
    Journal: Aust J Exp Biol Med Sci; 1985 Aug; 63 ( Pt 4)():431-8. PubMed ID: 3878700.
    Abstract:
    We describe a mycoplasma-free human fibrosarcoma cell line, MR-83, which grows readily in liquid culture and as clones in semi-solid agar with a plating efficiency of about 0.5%. It has a stable karyotype consisting of a modal number of 49-51 chromosomes, with two translocations and a deletion. The cell line shows resistance to adriamycin in semi-solid agar assay, and responds to Epidermal Growth Factor (EGF) by increased DNA synthesis, as measured by thymidine uptake.
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