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  • Title: [Complexes of monoclonal immunoglobulins of various classes with albumin and alpha 1-proteinase inhibitor].
    Author: Kotova TS, German GP, Chernokhvostova EV.
    Journal: Vopr Med Khim; 1985; 31(6):46-50. PubMed ID: 3879044.
    Abstract:
    Ability of monoclonal immunoglobulins (IgG, IgA, IgM and IgD) to develop complexes with albumin and alpha 1-proteinase inhibitor (alpha 1-PI) was studied using methods of immunoelectrophoresis, cross immunoelectrophoresis and immunoselection. High of proteins, producing complexes with albumin, was found among monoclonal IgA, IgM and IgG; alpha 1-PI formed complexes mainly with IgA and IgM. In healthy volunteers complexes of blood serum proteins were not found. Albumin and alpha 1-PI developed complexes most often with various molecules of monoclonal immunoglobulins. Ability to produce complexes did not depend on the type of the paraprotein.
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