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  • Title: Synthesis and pharmacological study of a series of 3(2H)-pyridazinones as analgesic and antiinflammatory agents.
    Author: Santagati NA, Duro F, Caruso A, Trombadore S, Amico-Roxas M.
    Journal: Farmaco Sci; 1985 Dec; 40(12):921-9. PubMed ID: 3879223.
    Abstract:
    The synthesis and the pharmacological evaluation of some 3(2H)-pyridazinone derivatives are reported. The compounds were screened for analgesic, antiinflammatory and antipyretic activities. All tested derivatives showed a higher analgesic activity than phenylbutazone, while being devoid of ulcerogenic action.
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