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  • Title: [Recombination between the fragile site Xq27 and the gene for coagulation factor IX].
    Author: Landoulsi A, de Blois MC, Guérin P, Rethoré MO, Lejeune J, Lucotte G.
    Journal: Ann Genet; 1985; 28(4):201-5. PubMed ID: 3879429.
    Abstract:
    Using the Taq I restriction polymorphism of a factor IX probe, we analysed the segregation of this gene and that of the fragile site Xq27. The ancestor of this family was a healthy carrier male. Of twelve informative meioses, at least four recombinations were detected. The hypothesis of a particular instability of the distal part the long arm of the X chromosome is reconsidered.
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