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  • Title: HLA, complement C2, C4, properdin factor B and glyoxalase types in South Indian diabetics.
    Author: Kirk RL, Ranford PR, Serjeantson SW, Thompson AR, Munirathnam Chetty SM, John L, Mohan V, Ramachandran A, Snehalatha C, Viswanathan M.
    Journal: Diabetes Res Clin Pract; 1985 Mar; 1(1):41-7. PubMed ID: 3879724.
    Abstract:
    A series of diabetic patients from 3 centres in South India have been tested for HLA A, HLA B, BF, C2, C4A, C4B and GLO types. For insulin-dependent diabetes mellitus (IDDM) patients there was a significant increase in HLA B8, of BF F and decrease of C4 A6. No significant variation in HLA, BF, C2 or GLO frequencies was found in non-insulin-dependent diabetes mellitus (NIDDM) patients, but there was a significant decrease in C4B 1 and an increase in C4B 2. The HLA and BF association in South Indian IDDM patients is very different from that reported previously in North India.
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