These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Afatinib-induced toxic epidermal necrolysis: A case report with a literature review.
    Author: Belančić A, Hlača N, Peternel S, Golčić M, Prpić-Massari L, Vlahović-Palčevski V.
    Journal: Br J Clin Pharmacol; 2024 Aug; 90(8):2030-2033. PubMed ID: 38803188.
    Abstract:
    We present a 70-year-old female patient diagnosed with epidermal growth factor receptor-mutated metastatic non-small cell lung cancer (T4N2M1a), who developed afatinib-induced toxic epidermal necrolysis (TEN). We have also performed a PubMed/Medline literature review to detect other possible cases of TEN/Stevens-Johnson syndrome associated with afatinib treatment and found only 5 other cases reported. To our best knowledge, this is the first case of afatinib-induced TEN successfully treated with cyclosporine.
    [Abstract] [Full Text] [Related] [New Search]