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  • Title: Shiga-like cytotoxin production by enteropathogenic Escherichia coli serogroups.
    Author: Cleary TG, Mathewson JJ, Faris E, Pickering LK.
    Journal: Infect Immun; 1985 Jan; 47(1):335-7. PubMed ID: 3880727.
    Abstract:
    The mechanism by which enteropathogenic Escherichia coli (EPEC) cause disease remains to be defined. We studied EPEC and non-EPEC strains of E. coli from stool specimens obtained from infants and adults for production of Shiga-like cytotoxin. Although it was common for healthy infants and adults to have cytotoxin-producing E. coli as part of the fecal flora, Shiga-like cytotoxin was detected more commonly and in greater amounts among EPEC than among other fecal E. coli. These results suggest a role for Shiga-like cytotoxin in the pathogenesis of EPEC-related gastroenteritis.
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