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  • Title: Levobunolol vs timolol for open-angle glaucoma and ocular hypertension.
    Author: Cinotti A, Cinotti D, Grant W, Jacobs I, Galin M, Silverstone D, Shin D, Esters J, Lee J, Bouchey R.
    Journal: Am J Ophthalmol; 1985 Jan 15; 99(1):11-7. PubMed ID: 3881032.
    Abstract:
    A group of 162 patients with chronic open-angle glaucoma or ocular hypertension were treated twice daily for up to 15 months with one of the following topical ophthalmic solutions: 0.5% levobunolol, 1% levobunolol, or 0.5% timolol. Overall mean reductions in intraocular pressure were 8 mm Hg for patients receiving 0.5% levobunolol or timolol and 8.2 mm Hg for patients receiving 1% levobunolol. There were no significant differences between levobunolol and timolol in mean reductions in intraocular pressure, percent of patients with adequately controlled intraocular pressure, or life-table estimates of the probability of successful treatment.
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