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  • Title: Toxoplasma gondii: redistribution of monoclonal antibodies on tachyzoites during host cell invasion.
    Author: Dubremetz JF, Rodriguez C, Ferreira E.
    Journal: Exp Parasitol; 1985 Feb; 59(1):24-32. PubMed ID: 3881269.
    Abstract:
    Immunodetection of protein P30, a major surface antigen of Toxoplasma gondii tachyzoites, by a specific monoclonal antibody has demonstrated a homogenous distribution of this antigen on the surface of intra- and extracellular tachyzoites at all stages of their endodyogenic development. On living zoites, no redistribution of anti-P30 was obtained, contrasting with the capping obtained with antiserum to T. gondii. Upon invasion of a host cell, however, most of the coat of anti-P30 was shed from preincubated zoites at the level of the moving junction governing the entry of the parasite into the host cell.
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