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  • Title: Normalization of urinary oxalate by taurine in glycolate-fed rats.
    Author: Talwar HS, Madiraju VS, Murthy SR, Nath R, Thind SK.
    Journal: Metabolism; 1985 Feb; 34(2):97-100. PubMed ID: 3881651.
    Abstract:
    Oral feeding of sodium glycolate (50 mg/d/rat for ten days) caused a significant (P less than 0.001) increase in oxalate and taurine excretion and a decrease in liver protein content (P less than 0.05), glycolic acid oxidase levels (P less than 0.01), and glycolic acid dehydrogenase levels (P less than 0.01) as compared to normal untreated rats. Taurine (100 mg/d/rat), when administered along with glycolate, prevented these effects of glycolate as evident from normal urinary excretion of oxalate, liver protein content, glycolic acid oxidase, and glycolic acid dehydrogenase levels in glycolate- plus taurine-fed animals.
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