These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Monoclonal antibody-defined human pancreatic cancer-associated antigens.
    Author: Schmiegel WH, Kalthoff H, Arndt R, Gieseking J, Greten H, Klöppel G, Kreiker C, Ladak A, Lampe V, Ulrich S.
    Journal: Cancer Res; 1985 Mar; 45(3):1402-7. PubMed ID: 3882225.
    Abstract:
    Three pancreatic cancer-associated antigens were characterized by use of monoclonal antibodies in immunobinding studies with various cellular and soluble target antigens, in immunoprecipitation, and in immunoperoxidase staining. C54-0 represents a tumor-associated Mr 122,000 antigen, which appears to be widely distributed on various epithelial tumors and to a lower extent on normal tissue. C1-N3 antigen exhibited a more restricted distribution, reacting with pancreatic and various gastrointestinal tract tumors as well as with chronically inflamed pancreatic tissue. The most specific antigen expression was observed for C1-P83 antigen, found on all exocrine tumors of the pancreas, but not on normal or chronically inflamed pancreatic tissue.
    [Abstract] [Full Text] [Related] [New Search]