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  • Title: The gastrointestinal absorption of PRD-92 Ea, a new anti-allergy drug.
    Author: Johnson AJ, Beets JL.
    Journal: Br J Clin Pharmacol; 1979 May; 7(5):511-3. PubMed ID: 38823.
    Abstract:
    1 The absorption of PRD-92 Ea, a new anti-allergy drug, was studied in volunteer subjects. 2 The 14C-labelled drug was administered orally and the radioactivity measured in plasma, urine and faeces. 3 Mean peak plasma concentration was 3.3 micrograms/ml, with a concentration of over 1 micrograms/ml maintained 4 h after administration. 4 The mean plasma half-life (T 1/2) was 114 min. 5 The mean percentage recovery in the urine was 9.5%. 6 Oral administration leads to significant and sustained plasma concentrations, and the oral route should be suitable for drug evaluation in clinical practice.
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