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  • Title: Antibiotic infection prophylaxis in gallbladder surgery--a prospective randomized study.
    Author: Harnoss BM, Hirner A, Krüselmann M, Häring R, Lode H.
    Journal: Chemotherapy; 1985; 31(1):76-82. PubMed ID: 3882356.
    Abstract:
    In the course of 1 year, 180 patients undergoing elective surgery for confirmed cholelithiasis were included in a prospective randomized study in which they either received 2 g of preoperatively applied ceftriaxon intravenously at the beginning of anesthesia or, as an alternative, no antibiotic at all. Infectious wound-healing disturbances occurred postoperatively in 11% in the control group and in no case in the prophylaxis group. The difference is statistically significant.
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