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  • Title: Fixed ratio combination of propranolol and bendrofluazide in the treatment of hypertension.
    Author: Pandhi P, Sharma BK, Sharma PL, Wahi PL.
    Journal: Int J Clin Pharmacol Ther Toxicol; 1985 Feb; 23(2):92-4. PubMed ID: 3886568.
    Abstract:
    The combination of beta adrenoceptor blocker, i.e. propranolol (80 mg) and a diuretic, i.e. bendrofluazide (2.5 mg) in a single capsule (Inderetic) produced an effective control of blood pressure in 12 out of 13 patients with mild and moderately severe hypertension in this single-blind study. Treatment for 12 weeks did not produce any changes in biochemical parameters and no change in ECG, except that a significant decrease in heart rate was observed. No serious side-effects were observed.
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