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  • Title: Indocyanine green clearance in critically ill patients.
    Author: Pollack DS, Sufian S, Matsumoto T.
    Journal: Surg Gynecol Obstet; 1979 Dec; 149(6):852-4. PubMed ID: 388703.
    Abstract:
    Forty-two consecutive patients were observed with the use of various biochemical and physiologic parameters. Attention was focused upon liver function, using serum glutamic-oxalacetic transaminase, alkaline phosphatase and bilirubin determinations as well as the plasma disappearance rate of indocyanine green. No difference was noted in serum glutamic-oxalacetic transaminase, alkaline phosphatase and bilirubin levels between survivors and nonsurvivors. However, there was a significant difference between these two groups as measured by the plasma disappearance rate of indocyanine green. A distinct cut-off point was present, and no survivor ever had a plasma disappearance rate of less than 6 per cent per minute.
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