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  • Title: On-mask detection of SARS-CoV-2 related substances by surface enhanced Raman scattering.
    Author: Liu X, Xie R, Li K, Zhu Z, Huang X, He Q, Sun Z, He H, Ge Y, Zhang Q, Chen H, Wang Y.
    Journal: Talanta; 2024 Sep 01; 277():126403. PubMed ID: 38878511.
    Abstract:
    We have developed a convenient surface-enhanced Raman scattering (SERS) platform based on vertical standing gold nanowires (v-AuNWs) which enabled the on-mask detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) related substances such as the Spike-1 protein and the corresponding pseudo-virus. The Spike-1 protein was clearly distinguished from BSA protein with an accuracy above 99 %, and the detection limit could be achieved down to 0.01 μg/mL. Notably, a similar accuracy was achieved for the pseudo-SARS-CoV-2 (pSARS-2) virus as compared to the pseudo-influenza H7N9 (pH7N9) virus. The sensing strategy and setups could be easily adapted to the real SARS-CoV-2 virus and other highly contagious viruses. It provided a promising way to screen the virus carriers by a fast evaluation of their wearing v-AuNWs integrated face-mask which was mandatory during the pandemic.
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