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  • Title: [Comparative pharmacological analysis of the mechanisms of thrombocyte aggregation induced by bacterial toxins and ADP].
    Author: Brill' GE, Shenkman BZ.
    Journal: Farmakol Toksikol; 1985; 48(2):82-5. PubMed ID: 3888666.
    Abstract:
    It has been demonstrated in experiments in vitro that exotoxin and endotoxin of Shigella sonnei produce the concentration-dependent rabbit platelet aggregation. Acetylsalicylic acid and theophylline substantially inhibit the ADP-induced aggregation and suppress to a less degree the effects of bacterial toxins. Monoiodine acetate inhibits aggregation induced by ADP and potentiates the aggregating action of toxins.
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