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  • Title: [Buflomedil and nicergoline in the targeted treatment of acute cerebral ischemia. Randomized comparative double blind study].
    Author: Bossi L.
    Journal: Minerva Med; 1985 May 19; 76(21):1005-18. PubMed ID: 3889723.
    Abstract:
    Acute cerebral ischaemia may take considerable advantages of an adequate intensive therapy associated with a specific treatment of cerebral oedemas, especially in terms of mortality-rate reduction. Moreover, target treatment of acute cerebral ischaemia may produce excellent results in severe cases selected by means of EEG-chronospectrography. Double-blind, randomized comparison between nicergolin and buflomedil especialls showed that the latter reduces mortality three times as much as nicergolin, and leads to a 200% increment in the complete recovery of the "functio laesa", limited to those cases, which showed an appreciable improvement following EEG-chronospectrographical survey.
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