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  • Title: [Measurement of inner ear circulation using radioactive indicators].
    Author: Friedrich G, Nicoletti R, Fueger GF.
    Journal: Laryngol Rhinol Otol (Stuttg); 1985 Apr; 64(4):214-6. PubMed ID: 3892206.
    Abstract:
    To clarify the possibility of measuring the inner ear blood flow by radionuclide imaging, we used a skull phantom and a scintillation camera and found that a concentration difference of at least 100: 1 between the inner ear and the background is needed for external detection. Similar concentration differences can be found in aminoglycosid antibiotics because of their special pharmacokinetic characteristics. We believe, therefore, that with an appropriate radioactive indicator, such as labelled aminoglycoside or labelled (99mTc, 123J)-inulin, it would be possible to measure the inner ear blood flow in a non-invasive and selective way.
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