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  • Title: A change of threonine 266 to isoleucine in the lac permease of Escherichia coli diminishes the transport of lactose and increases the transport of maltose.
    Author: Markgraf M, Bocklage H, Müller-Hill B.
    Journal: Mol Gen Genet; 1985; 198(3):473-5. PubMed ID: 3892229.
    Abstract:
    The DNA sequence of several functionally interesting lac permease mutants of Escherichia coli has been determined. The phenotypes of the mutant permeases were described by Mieschendahl et al. (1981). The following exchanges are noteworthy: tyr to asp in codon 26 in Y-K MUB 7; thr to ile in codon 266 in Y-K AJ 33; gly to asp in codon 262 in Y-D 3 and in Y-D 4.
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