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  • Title: Pathophysiology of acute mountain sickness and high altitude pulmonary oedema: an hypothesis.
    Author: Sutton JR, Lassen N.
    Journal: Bull Eur Physiopathol Respir; 1979; 15(5):1045-52. PubMed ID: 389325.
    Abstract:
    We review the evidence that acute mountain sickness (AMS) and high altitude pulmonary oedema (HAPO) occur together more often than is realized. We hypothesize that AMS and HAPO have a common pathophysiological basis: both are due to increased pressure and flow in the microcirculation, causing oedema in the brain and oedema in the lungs.
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