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  • Title: An exhaled breath gas sensor system for near-infrared ammonia measurement and kidney diagnostics.
    Author: Zheng K, Zhang L, Leng S, Xi Z, Zheng C, Wang Y, Tittel FK.
    Journal: Spectrochim Acta A Mol Biomol Spectrosc; 2024 Nov 15; 321():124625. PubMed ID: 38950480.
    Abstract:
    Breath analysis enables rapid, noninvasive diagnosis of human health by identifying and quantifying exhaled biomarker. Here, we demonstrated an exhaled breath sensing method using the near-infrared laser spectroscopy, and sub parts-per-million (ppm) level ammonia detection inside the exhaled gas was achieved employing a distributed feedback laser centered at 1512 nm and Kalman filtering algorithm. Integration of the ammonia sensor was realized for exhaled breath analysis of kidney patients, and a dual operation mechanism with static and dynamic modes was proposed to make this method applicable for real-time and comprehensive pre-diagnosis of kidney disease.
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