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  • Title: Biosynthesis of thiamin. The precursor of the five-carbon unit of the thiazole moiety.
    Author: Yamada K, Yamamoto M, Hayashiji M, Tazuya K, Kumaoka H.
    Journal: Biochem Int; 1985 Apr; 10(4):689-94. PubMed ID: 3896243.
    Abstract:
    The precursor of the thiazole moiety of thiamin in Candida utilis was identified. Radioactive C-2, 3, 4, 5 and 6 of glucose was incorporated into C-4', 4, 5, 5' and 5" of the thiazole. This experiment shows that the precursor of the five carbon unit of thiazole is a 5-carbon compound such as ribose or ribulose derived from glucose.
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