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  • Title: The management of elderly patients with acute lower respiratory tract infections: a comparison of pivampicillin and amoxycillin.
    Author: Admani AK, Somasundram U, Singh I.
    Journal: Curr Med Res Opin; 1985; 9(8):536-41. PubMed ID: 3896663.
    Abstract:
    In a randomized trial, the efficacy of pivampicillin (500 mg or 1 g twice daily) was compared with that of amoxycillin (250 mg or 500 mg 3-times daily) in 43 elderly hospitalized patients with bronchopneumonia (32 patients) or an acute exacerbation of chronic bronchitis (11 patients). Overall, 13 (57%) out of the 23 patients taking pivampicillin were cured, and the remaining 10 subjects were improved. In the amoxycillin group, there were 9 (45%) cures, 9 improved and 2 failures of treatment. One patient in each treatment group had mild side-effects. Forty (93%) out of the 43 patients in the study expressed a preference for an antibiotic that was given twice daily as opposed to one where 3 doses were taken each day.
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