These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A covalent-organic framework-based platform for simultaneous smartphone detection and degradation of aflatoxin B1.
    Author: Zhou L, Duan X, Dai J, Ma Y, Yang Q, Hou X.
    Journal: Talanta; 2024 Oct 01; 278():126505. PubMed ID: 38968658.
    Abstract:
    This study developed a smartphone-based biosensor that could simultaneously detect and degrade aflatoxin B1 (AFB1). A donor-acceptor covalent organic framework (COF) was bound onto the surface of stainless-steel mesh (SSM) via the in-situ synthesis, which was used to immobilize the aptamer (Apt) to specifically capture AFB1 and was also as a photocatalyst to degrade AFB1. Au@Ir nanospheres were synthesized, which exhibited better peroxidase catalytic activity (Km=5.36 × 10-6 M, Vmax=3.48 × 10-7 Ms-1, Kcat=1.00 × 107 s-1) than Ir@Au nanospheres, so Au@Ir nanospheres were linked with Apt2 to be utilized as the signal probe. The density functional theory calculation also described that Au@Ir nanospheres possessed the lower energy barriers to decompose H2O2 than Ir@Au nanospheres. Coupled with the "Color Picker" application in the smartphone, the established "sandwich-structure" colorimetric method exhibited a linear range of 0.5-200 μg L-1 and a detection limit of 0.045 μg L-1. The photocatalytic capacity of SSM/COF towards AFB1 was investigated and the degradation rate researched 81.14 % within 120 min under the xenon lamp irradiation, and the degradation products were validated by ESI-MS. It was applied for the detection of AFB1 in peanuts, corn, and wheat samples. Recoveries were ranging from 77.90 % to 112.5 %, and the matrix effect was 75.10-111.6 %. Therefore, the smartphone-based biosensor provided a simple, fast, and sensitive platform for the detection of AFB1, and meanwhile could realize the efficient degradation of AFB1.
    [Abstract] [Full Text] [Related] [New Search]