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  • Title: [Conjunctival impression in the keratoconjunctivitis sicca syndrome].
    Author: Royer J, Tabatabay C, Deschamps F.
    Journal: Klin Monbl Augenheilkd; 1985 Jun; 186(6):513-4. PubMed ID: 3900542.
    Abstract:
    Cytological study is extremely useful in supplementing clinical findings in various conjunctival and corneal conditions. The authors describe a simple, reproducible, and painless method - impression cytology - for removing conjunctival tissue. It is cheap and quick, and can also be used for outpatients. The sample is spread flat on a light microscope slide and cytologically evaluated, e.g., with regard to perilimbal distribution of the mucus cells, cell nucleus-cytoplasm ratio and serpiginous aspect of the chromatin. The method permits more objective evaluation than is possible with conventional biopsy methods. It is particularly suitable in dry-eye syndrome and hypersecretion of the mucus cells. By repeating the procedure information can be obtained about the course of the disease and the efficacy of therapy.
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