These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: Insulin binding on erythrocytes in unsatisfactorily controlled obese diabetics (type 2) and nonobese diabetics (type 1). Author: Páv J, Hilgertová J, Srámková J. Journal: Exp Clin Endocrinol; 1985 Aug; 86(1):53-60. PubMed ID: 3902484. Abstract: Insulin binding to receptors on erythrocytes was studied in 2 groups of poorly controlled diabetics, i.e. a) 9 noninsulin dependent obese diabetics, b) 8 insulin-dependent nonobese diabetics, and in a group of 10 nondiabetic control subjects. The mean binding value in obese diabetics-type 2 was significantly lower than in controls (4.5 +/- 0.4% vers. 7.3 +/- 0.4%), the difference between the control mean value and the mean value in diabetics-type 1 (6.3 +/- 0.8%) was not statistically significant. Compared with the controls, lower numbers of insulin receptors per cell were found in both groups of diabetics (162 +/- 9 vers. 60 +/- 13 and 88 +/- 13, resp.). The lower number of receptors in diabetics-type 1 seems to be counterbalanced, at least partly, by their higher affinity.[Abstract] [Full Text] [Related] [New Search]