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  • Title: A NIR-II absorbing conjugated polymer based on tetra-fused isoindigo with ultrahigh photothermal conversion efficiency for cancer therapy.
    Author: Wu J, Rao M, Zhu Y, Wang P, Chen M, Qu Y, Zheng X, Jiang Y.
    Journal: Chem Commun (Camb); 2024 Aug 06; 60(64):8427-8430. PubMed ID: 39034822.
    Abstract:
    A conjugated polymer, P4TTD-DPP, based on tetra-fused isoindigo-alt-diketopyrrolopyrrole, has been synthesized as a photothermal therapeutic nanotransducer within the near-infrared-II (NIR-II) window. P4TTD-DPP exhibits a notable mass extinction coefficient of 62.8 L g-1 cm-1 at 1064 nm. Additionally, P4TTD-DPP nanoparticles demonstrate remarkable photothermal conversion efficiency of 91.5% at 1064 nm and exhibit excellent anticancer efficacy under photothermal conditions.
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