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  • Title: [Demonstration of lipoprotein anomalies in leptospirosis. Prospective study in 10 patients].
    Author: Estavoyer JM, Ottignon Y, Stimmesse B, Cardot N, Boillot A, Couetdic G.
    Journal: Pathol Biol (Paris); 1985 Oct; 33(8):819-23. PubMed ID: 3903619.
    Abstract:
    Abnormalities of lipid metabolism have never been shown in human leptospirosis. A prospective study of plasma lipids was performed in 10 consecutive patients with leptospirosis. Significant increase of triglycerides with low levels of the high-density lipoproteins and cholesterol fraction was observed in 8 patients. Electrophoresis of lipoproteins showed a fusion of beta and pre-beta lipoproteins and a marked decrease of alpha lipoproteins. The respective role of bacteria, liver and kidney could be suggested to explain these abnormalities of lipoproteins in leptospirosis.
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