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  • Title: The therapeutic actions of theophylline in preterm ventilated infants.
    Author: Greenough A, Elias-Jones A, Pool J, Morley CJ, Davis JA.
    Journal: Early Hum Dev; 1985 Oct; 12(1):15-22. PubMed ID: 3905342.
    Abstract:
    40 preterm, ventilated infants (gestational ages 24-33 weeks) were entered into a double-blind randomised trial to assess the effect of oral theophylline on lung function and ventilator dependence. Theophylline administration was associated with a significant improvement in compliance (P less than 0.05) and hastened weaning from ventilation (P less than 0.01).
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