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Title: Mutation affecting resistance of Escherichia coli K12 to nalidixic acid. Author: Hrebenda J, Heleszko H, Brzostek K, Bielecki J. Journal: J Gen Microbiol; 1985 Sep; 131(9):2285-92. PubMed ID: 3906038. Abstract: A new mutation, nalD, determining resistance of Escherichia coli to nalidixic acid (NAL) is reported. The nalD mutant described is resistant to NAL at 37 degrees C but sensitive at 30 degrees C. It is defective in penetration of NAL and glycerol through the outer membrane at 37 degrees C. The nalD mutation is located half-way between 89 and 89.5 min on the E. coli genetic map.[Abstract] [Full Text] [Related] [New Search]