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  • Title: Chemotherapy plus immunotherapy for patients with primary and metastatic brain tumors.
    Author: Knerich R, Robustelli della Cuna G, Butti G, Pavesi L, Adinolfi D, Preti P, Locatelli D.
    Journal: J Neurosurg Sci; 1985; 29(1):19-24. PubMed ID: 3906050.
    Abstract:
    The authors report two clinical trials concerning chemotherapy and immunotherapy combined in the treatment of primary and metastatic brain tumors. In the first study bacillus Calmette-Guerin (BCG) and in the second Levamisole (LMS) were utilized as immunostimulating agents. Chemotherapy was performed with BCNU or CCNU in association with surgery and/or radiotherapy. The immunological response was obtained but immunotherapy failed to demonstrate any significant effect on survival.
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