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  • Title: The selectivity of action of the aspartic-proteinase inhibitor IA3 from yeast (Saccharomyces cerevisiae).
    Author: Dreyer T, Valler MJ, Kay J, Charlton P, Dunn BM.
    Journal: Biochem J; 1985 Nov 01; 231(3):777-9. PubMed ID: 3907626.
    Abstract:
    The ability of the aspartic-proteinase inhibitor IA3 from yeast (Saccharomyces cerevisiae) to affect the activities of a range of mammalian and microbial aspartic proteinases was examined. The inhibitor appeared to be completely selective in that only the aspartic proteinase A from yeast was inhibited to any significant extent. IA3 thus represents the first example of a totally specific, naturally occurring, aspartic-proteinase inhibitor.
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