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  • Title: [Reversible renal insufficiency and arterial hypertension after renal transplantation: role of transplant artery stenosis and a captopril-furosemide combination].
    Author: Suc JM, Vernier I, Durand D, Giraud P, Segonds-Modesto A, Sarramon JP.
    Journal: Nephrologie; 1985; 6(3):155-8. PubMed ID: 3908959.
    Abstract:
    Acute renal failure after captopril therapy in patients with transplant artery stenosis is well known. The study of a new observation may stress three particular points: 1) Diagnosis may be difficult just after transplantation in case of initial acute renal failure. 2) Renal function rapidly improved after withdrawing captopril and furosemide; after surgical treatment of the stenosis, a new course of captopril therapy was possible without any decrease of glomerular filtration rate. 3) A critical fall in filtration fraction seems to be the essential mechanism of renal failure, but specific interstitial lesions of the transplant showed on kidney biopsies, might be discussed.
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