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  • Title: Use of chloroquine-treated granulocytes and platelets in the diagnosis of immune cytopenias.
    Author: Metcalfe P, Minchinton RM, Murphy MF, Waters AH.
    Journal: Vox Sang; 1985; 49(5):340-5. PubMed ID: 3909637.
    Abstract:
    A chloroquine modification of the fluorescent antiglobulin technique has been used to demonstrate cell-specific antibodies in the presence of HLA antibodies. This is of particular value in the diagnosis of alloimmune neonatal thrombocytopenia and neutropenia, post-transfusion purpura, and in the investigation of febrile non-haemolytic transfusion reactions and of patients refractory to platelet transfusions.
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