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  • Title: [Biosynthesis of lytic enzymes in a mixed culture of actinomycetes and yeasts].
    Author: Iakovleva EP, Kuz'mina ED.
    Journal: Antibiot Med Biotekhnol; 1985 Dec; 30(12):887-93. PubMed ID: 3909950.
    Abstract:
    It was shown that S. levoris, an organism producing levorin, formed lytic enzymes in monocultures and in mixed cultures with C. tropicalis. Stimulation of the antibiotic production in the mixed cultures depended on the activity of lysoenzymes. When their activity was lowered by addition of cobalt salts to the medium the stimulating effect on the antibiotic synthesis was not observed. In cultivation of S. levoris and C. tropicalis it is necessary to provide optimal conditions for the growth of the yeasts and synthesis of the biostimulator by them and also for the simultaneous growth of the actinomycete and production of the antibiotic and lytic enzymes by it.
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