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Title: Correlation between a positive gallbladder culture and subsequent wound infection after biliary surgery--a retrospective study of 840 patients. Author: van Leeuwen PA, Keeman JN, Butzelaar RM, Van den Bogaard AE. Journal: Neth J Surg; 1985 Dec; 37(6):179-82. PubMed ID: 3911113. Abstract: The possible correlation between a positive culture of samples from the gallbladder wall and/or bile at the time of cholecystectomy and subsequent wound infections was retrospectively studied in a series of 840 patients. Positive cultures were present in 138 patients (16.4) and 19 different bacterial species could be identified. Cultured bile showed Escherichia coli in 36% of cases. The wound infection rate was 9% (72 patients) with Staphylococcus aureus cultured from the infected wounds in 64%. Fifty-eight of these 72 patients (80%) were at high risk. In contrast with the literature, no correlation existed between a positive bile culture and subsequent wound infection. In view of these results there is no need to evaluate a Gram-stain during surgery. Antimicrobial prophylaxis should be restricted to high-risk patients and the antibiotics used must be effective against exogenic wound contaminants.[Abstract] [Full Text] [Related] [New Search]