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  • Title: The effect of changes in intra-compartmental bioimpedance measurements with early intra-dialytic hypotension during haemodialysis.
    Author: Haroon S, Davenport A.
    Journal: Int J Artif Organs; 2024 Nov; 47(11):802-809. PubMed ID: 39166424.
    Abstract:
    INTRODUCTION: Intra-dialytic hypotension (IDH) remains the commonest problem associated with routine haemodialysis treatments. Fluid shifts from intracellular(ICW) and extracellular(ECW) compartments to refill plasma volume during haemodialysis with ultrafiltration. METHODS: We studied the effect of relative changes in ICW and ECW indifferent body segments using multifrequency segmental bioimpedance during haemodialysis and IDH episodes. RESULTS: Of 42 haemodialysis patients,16 patients (38.1%) developed IDH within the first hour of dialysis. Patients with and without early IDH were well-matched for demographics and starting bioimpedance measurements. However, after 60 min, the relative change in in ECW/ICW ratio between the non-fistula arm and leg was significantly different for the early IDH group median -1.07 (-3.33 to 0.8) versus 0.61 (-0.78 to 1.8), p < 0.05, whereas there no differences in ultrafiltration rate, relative blood volume monitoring or on-line clearance. CONCLUSION: Monitoring serial changes in fluid status in different body compartments with bioimpedance may potentially prevent IDH in the future.
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