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  • Title: Endothelium influences coronary and aortic vasomotion by release of an unstable humoral factor.
    Author: Griffith TM, Edwards DH, Lewis MJ, Henderson AH.
    Journal: Adv Myocardiol; 1985; 6():137-53. PubMed ID: 3922024.
    Abstract:
    Using an isolated perfused coronary-artery preparation, we have demonstrated the ability of endothelium inhibit markedly to vasomotion in rabbit coronary arteries. Using a bioassay system, we have shown this effect to be mediated via the release of an unstable humoral agent (t 1/2 approximately equal to 6 sec) from endothelial cells, and we have partially characterized its chemical nature.
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