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  • Title: Contemporary Statistics of Acute Ischemic Stroke and Transient Ischemic Attack in 2021: Insights From the CRCS-K-NIH Registry.
    Author: Kim DY, Park TH, Cho YJ, Park JM, Lee K, Lee M, Lee J, Bae SY, Hong DY, Jung H, Ko E, Guk HS, Kim BJ, Kim JY, Kang J, Han MK, Park SS, Hong KS, Park HK, Lee JY, Lee BC, Yu KH, Oh MS, Kim DE, Gwak DS, Lee SJ, Kim JG, Lee J, Kwon DH, Cha JK, Kim DH, Kim JT, Choi KH, Kim H, Choi JC, Kim JG, Kang CH, Sohn SI, Hong JH, Park H, Lee SH, Kim C, Shin DI, Yum KS, Kang K, Park KY, Jeong HB, Park CY, Lee KJ, Kwon JH, Kim WJ, Lee JS, Bae HJ, CRCS-K Investigators.
    Journal: J Korean Med Sci; 2024 Sep 02; 39(34):e278. PubMed ID: 39228188.
    Abstract:
    This report presents the latest statistics on the stroke population in South Korea, sourced from the Clinical Research Collaborations for Stroke in Korea-National Institute for Health (CRCS-K-NIH), a comprehensive, nationwide, multicenter stroke registry. The Korean cohort, unlike western populations, shows a male-to-female ratio of 1.5, attributed to lower risk factors in Korean women. The average ages for men and women are 67 and 73 years, respectively. Hypertension is the most common risk factor (67%), consistent with global trends, but there is a higher prevalence of diabetes (35%) and smoking (21%). The prevalence of atrial fibrillation (19%) is lower than in western populations, suggesting effective prevention strategies in the general population. A high incidence of large artery atherosclerosis (38%) is observed, likely due to prevalent intracranial arterial disease in East Asians and advanced imaging techniques. There has been a decrease in intravenous thrombolysis rates, from 12% in 2017-2019 to 10% in 2021, with no improvements in door-to-needle and door-to-puncture times, worsened by the coronavirus disease 2019 pandemic. While the use of aspirin plus clopidogrel for non-cardioembolic stroke and direct oral anticoagulants for atrial fibrillation is well-established, the application of direct oral anticoagulants for non-atrial fibrillation cardioembolic strokes in the acute phase requires further research. The incidence of early neurological deterioration (13%) and the cumulative incidence of recurrent stroke at 3 months (3%) align with global figures. Favorable outcomes at 3 months (63%) are comparable internationally, yet the lack of improvement in dependency at 3 months highlights the need for advancements in acute stroke care.
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