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  • Title: Genetic mapping and characterization of Pseudomonas aeruginosa mutants that hyperproduce exoproteins.
    Author: Björklind A, Wretlind B, Möllegård I, Schad PA, Iglewski BH, Cox CD.
    Journal: J Bacteriol; 1985 Jun; 162(3):1329-31. PubMed ID: 3922951.
    Abstract:
    We isolated two mutants of Pseudomonas aeruginosa PAO with defective iron uptake. In contrast to the wild-type strain, the mutants produced extracellular protease activity in media containing high concentrations of salts or iron and hyperproduced elastase, staphylolytic enzyme, and exotoxin A in ordinary media (Xch mutants). The mutations were located in the 55' region of the chromosome, between the markers met-9011 and pyrD.
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